Run Python scripts on the cloud with uv and Coiled

It’s been fun to see all the uv examples lately on this sub, so thought I’d share another one.

For those who aren’t familiar, uv is a fast, easy to use package manager for Python. But it’s a lot more than a pip replacement. Because uv can interpret PEP 723 metadata, it behaves kind of like npm, where you have self-contained, runnable scripts. This combines nicely with Coiled, a UX-focused cloud compute platform. You can declare script-specific dependencies with uv add –script and specify runtime config with inline # COILED comments.

Your script might end up looking something like:

# COILED container ghcr.io/astral-sh/uv:debian-slim # COILED region us-east-2 # /// script # requires-python = « >=3.12 » # dependencies = [ # « pandas », # « pyarrow », # « s3fs », # ] # ///

And you can run that script on the cloud with:

uvx coiled batch run uv run my-script.py

Compare that to something like AWS Lambda or AWS Batch, where you’d typically need to:

Package your script and dependencies into a ZIP file or build a Docker image Configure IAM roles, triggers, and permissions Handle versioning, logging, or hardware constraints

Here’s the full video walkthrough: https://www.youtube.com/watch?v=0qeH132K4Go